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  1. CREST syndrome - Wikipedia

    CREST syndrome, also known as the limited cutaneous form of systemic sclerosis (lcSSc), is a multisystem connective tissue disorder. The acronym "CREST" refers to the five main …

  2. Scleroderma - Wikipedia

    Symptoms may include areas of thickened skin, stiffness, feeling tired, and poor blood flow to the fingers or toes with cold exposure. [1] One form of the condition, known as CREST syndrome, …

  3. Systemic scleroderma - Wikipedia

    Signs and symptoms C alcinosis, R aynaud's phenomenon, E sophageal dysfunction, S clerodactyly, and T elangiectasia (CREST syndrome) are associated with limited scleroderma. …

  4. Sclerodactyly - Wikipedia

    Sclerodactyly is one component of the limited cutaneous form of systemic sclerosis (lcSSc), also known as CREST syndrome (CREST is an acronym that stands for calcinosis, Raynaud's …

  5. Esophageal motility disorder - Wikipedia

    Achalasia Diffuse esophageal spasm Nutcracker esophagus Hypertensive lower esophageal sphincter An esophageal motility disorder can also be secondary to other diseases. [1] For …

  6. Calcinosis cutis - Wikipedia

    Calcinosis cutis is an uncommon condition marked by calcium buildup in the skin and subcutaneous tissues. Calcinosis cutis can range in intensity from little nodules in one area of …

  7. Anti-Scl-70 antibodies - Wikipedia

    Anti-Scl-70 (also called anti-topoisomerase I after the type I topoisomerase target [1]) is an anti-topoisomerase antibody -type of anti-nuclear autoantibodies, seen mainly in diffuse systemic …

  8. Telangiectasia - Wikipedia

    Telangiectasias, aside from presenting in many other conditions, are one of the features of the acronymically named CREST syndrome, a form of systemic scleroderma. The syndrome …