The histone proteins of complex cells are named H2A, H2B, H3 and H4. They are assembled into groups of eight, around which a ...

Researchers unveil the inner mechanisms of the most intricate and complex molecular machine in human biology. Scientists at ...

An international team of researchers has provided a genetic diagnosis for 30 individuals whose condition was undiagnosed for years despite extensive clinical or genetic testing.

The good news is that drugs called CHK1 inhibitors were found to selectively destroy tumor cells containing ecDNA in mice ...

giving some cells a competitive edge (DOI: 10.1038/s41586-024-07861-8). Finally, the researchers describe a way to exploit ...

Katelyn Chew looks at how new research is helping us understand the ability of DNA to reshuffle in the nucleus using CRISPR ...

Transcription activation of genes by estrogens is driven by enhancers, which are often located within the same Topologically Associating Domain (TAD) as non-targeted promoters. We investigated how ...

Professor Carsten Carlberg has published a comprehensive new textbook, "Gene Regulation and Epigenetics: How Science Works," ...

In the current study, Hartl found this defective repair mechanism is linked to a non-functional p53 gene, which plays a key role in regulating the cell cycle and in repairing DNA. "If there is no ...

Researchers at Sinai Health have discovered that DNA elements known as transposons, which may travel throughout the genome, ...

Further experiments showed that these LINE-1 message molecules act as a scaffold to organize the DNA in the 3D space of the cell's nucleus. They help move chromosome 19-;home to crucial genes for ...

Labroots and the Cell & Gene Therapy planning committee are thrilled to announce the debut of the Cell & Gene Therapy Virtual Event Series, premiering exclusively online October 16th, 2024. Join us as ...