One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...

If stretched out, human DNA would be about 2 meters long. For this long strand to fit inside the cell nucleus, which is about ...

Although it also performs some functions in men, estrogen, the main female sex hormone, is involved in a myriad of processes, ...

A team of researchers has generated one of the most detailed 3D maps of human chromosomes, cataloging over 140,000 DNA looping interactions.

Noah A. Dusseau is in the Department of Physiology, College of Natural Science, Michigan State University, East Lansing, Michigan 48824, USA. Read the paper: Genetic elements promote retention of ...

The genetic heritage is not a simple, static list inside the cell nucleus. It unfolds into a dynamic architecture whose intimate folds govern the destiny of cells. A mapping of ...

Estrogens, the main female sex hormone, although they also perform some functions in men, are involved in a myriad of ...

The 4D map, which includes more than 140,000 folds and loops for every type of cell, illustrates how human DNA is organized not only in space but also in time. This information is crucial ...

New 3D genome maps reveal how DNA folding controls gene activity, offering fresh clues into disease and cell function.

UC San Diego researchers uncover enzyme behind cancer genome chaos, pointing to potential therapies for aggressive tumors.

UC San Diego scientists have identified the enzyme that shatters cancer genomes and helps them evolve to resist treatment, solving a longstanding mystery in the molecular biology of cancer.