The histone proteins of complex cells are named H2A, H2B, H3 and H4. They are assembled into groups of eight, around which a ...

The good news is that drugs called CHK1 inhibitors were found to selectively destroy tumor cells containing ecDNA in mice ...

Professor Carsten Carlberg has published a comprehensive new textbook, "Gene Regulation and Epigenetics: How Science Works," ...

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), Volume 16, Issue 20 on October 17, 2024, entitled, "Werner syndrome RECQ ...

Transcription activation of genes by estrogens is driven by enhancers, which are often located within the same Topologically Associating Domain (TAD) as non-targeted promoters. We investigated how ...

Scientists have discovered a way to target elusive circular fragments of DNA that drive the survival of some of the most aggressive cancers, paving the way for future treatments.

A trio of research papers from Stanford Medicine researchers and their international collaborators transforms scientists' understanding of how small DNA circles—until recently dismissed as ...

Tiny circles called ecDNA are critical in cancer development and drug resistance. An international team publishes landmark studies detailing new findings and potential therapies.

What is DNA, and how does it work? You don't need a degree in genetics to understand. Here, we'll give an overview of DNA and ...

Katelyn Chew looks at how new research is helping us understand the ability of DNA to reshuffle in the nucleus using CRISPR ...

Several important differences exist between oncogenes and tumor suppressor genes in cancer. In general, oncogenes are dominant. In our bodies, we have two sets of each of our chromosomes and ...