Understanding the interaction between light and matter at the smallest scales (angstrom scale) is essential for advancing technology and materials science. Atomic-scale structures, such as defects in ...

Spatial biology captures molecular complexity by preserving the physical context of cells in their native environments. From deciphering RNA dynamics within stress granules to scaling molecular ...

To unravel the complexities of biological phenomena, scientists have long relied on microscopy to visualize the intricate details of their specimens, including tissue architecture, cell morphology, ...

Microscopy is an imaging technique that enables us to see a world that would otherwise be invisible to us. Once upon a time, visualizing cells, microbes and other entities not perceptible to the naked ...

Even those who maintain that super-resolution microscopy is a powerful tool of biological discovery have admitted that it may have a bit of an image problem. For example, in a recent review, several ...

Researchers from the University of Science and Technology of China (USTC) have unveiled a planar optical device that significantly enhances the capabilities of dark-field microscopy, achieving ...

A new tissue expansion method enables scientists to use mass spectrometry imaging to simultaneously detect hundreds of molecules at the single cell level in their native locations. For biologists, ...

Ultrasound examination has become a key tool in clinical diagnosis due to its safety, non-invasiveness, lack of ionizing radiation, and ease of use. However, traditional ultrasound imaging faces a ...

3D spatial biology addresses one of the field's most persistent blind spots: the loss of depth. Most spatial transcriptomics platforms generate data from a single tissue section, a thin slice ...

When single-molecule super-resolution microscopes were first commercialized some 15 years ago, they made headlines for their ability to resolve individual molecules and structures at the nanometer ...