There’s a good chance that Berkshire Hathaway’s stock will lag the S&P 500 in the coming years. This is a matter of simple probabilities, and not a criticism of Berkshire Hathaway Chairman and Chief Executive Warren Buffett or his designated successors.

While some investors are likely to focus on the biggest-dollar moves made in the fourth quarter, such as the continued aggressive selling of No. 3 holding, Bank of America, the more telling action might be Berkshire's complete exit from the Vanguard S&P 500 ETF ( VOO 0.24%) and SPDR S&P 500 ETF Trust ( SPY 0.23%).

Investors are awaiting Berkshire Hathaway Chairman Warren Buffett’s annual investor letter, in which he typically expounds on Berkshire’s performance along with anecdotes and vignettes about investing and life.

Berkshire entered a new holding in Constellation Brands during the fourth quarter of 2024. Buffett's firm also trimmed its position in Bank of America.

Key Takeaways Warren Buffett's Berkshire Hathaway is set to report fourth-quarter earnings on Saturday.Buffett's annual shareholder letter, which investors look to for commentary on investments and the economy,