In a study published in the Clinical and Translational Medicine, a Nanjing University research group evaluated the on- and off-target effects of self-assembled siRNA delivery system. RNA interference ...

In liver, lipid nanoparticles (LNPs) were first used to deliver patisiran, currently the only siRNA drug on the market that uses this technology platform. The animal POC studies of LNP-mediated siRNA ...

An ideal nucleic-acid transfection system should combine the physical and chemical characteristics of cationic lipids and linear polymers to decrease cytotoxicity and uptake limitations. Previous ...

New RNA-based active agents reliably protect plants against the Cucumber mosaic virus (CMV), the most common virus in agriculture and horticulture. They were developed by researchers at the Martin ...