Cellular senescence, a state in which cells stop proliferating, is often associated with aging and pathologies like cancer. 1 ...

A small cut that would close in days on a 30-year-old can linger for weeks on someone in their 70s. Surgical incisions heal ...

Deep inside the brain, a cluster of stem cells no larger than a grain of rice has been quietly running the body’s aging clock ...

Targeting senescent cells with dasatinib–quercetin preserves disc structure and modulates degeneration-associated ...

Targeting senescent cells with dasatinib-quercetin preserves disc structure and modulates degeneration-associated pathways in a mouse model.

Cell senescence — a state of irreversible cell-growth arrest — has important physiological functions and is a key driver of ageing. The articles in this Focus explore the molecular mechanisms that ...

With age, teeth get increasingly brittle and susceptible to damage from tooth decay, which can eventually lead to tooth loss.

Senescent cells, which are damaged and inflammatory, contribute significantly to aging. Researchers at the Max Planck Institute for Biology of Aging have found that worms can enter a senescent-like ...

Senescence is a highly controlled process that plays a key role in plant development and survival. It allows for the appropriate re-allocation of nutrient resources at specific developmental stages or ...

Scientists are uncovering a surprising truth about aging cells: some may damage the body, while others help protect it. The discovery is fueling a new wave of precision anti-aging therapies aimed at ...

Researchers identified a stem cell population that declines during aging, but anti-aging drugs may help restore their ...

Metabolic reprogramming and circadian disruption drive cellular senescence. Discover how repurposing vutiglabridin to target ...