Membrane proteins are vital for cellular signaling, transport, and communication, making them attractive drug targets despite their challenging properties. Advances in mass spectrometry have enabled ...

Fragment-based drug design (FBDD) has led to a revolution in contemporary drug discovery, facilitating a bottom-up approach to the identification and evolution of bioactive small molecules into viable ...

All biological function is dependent on how different proteins interact with each other. Protein-protein interactions ...

Nanopores are tiny, nanometer-scale apertures that are synthetically produced in manufactured materials as well as biological membranes. They allow ions or molecules to pass through and have been ...

Hundreds of protein-ligand interactions have been identified through a collaboration between the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences and Pfizer. Georg ...