Please provide your email address to receive an email when new articles are posted on . BOSTON — Healio spoke with James L. Boyer, MD, about phase 3 findings from the RESPONSE trial and the ELATIVE ...

Please provide your email address to receive an email when new articles are posted on . In a video exclusive, Gideon Hirschfield, PhD, FRCP, of the University of Toronto, reported the potential of ...

Sclerosing cholangitis and primary biliary cirrhosis, which is now called primary biliary cholangitis (PBC), are chronic cholestatic liver diseases, but they differ in their causes, affected bile ...

Patients with primary biliary cholangitis who are treated with the only approved first-line therapy commonly have persistently elevated levels of alkaline phosphatase, bilirubin, or both. New research ...

Seladelpar is an oral, selective peroxisome proliferator-activated receptor delta agonist. Treatment with seladelpar was associated with an improvement in cholestatis markers in patients with primary ...

Findings showed a statistically significantly greater proportion of saroglitazar-treated patients achieved a biochemical response vs placebo (treatment difference, 48.5%; P .001). Topline data were ...

(RTTNews) - Primary Biliary Cholangitis is a rare, progressive, chronic autoimmune disease of the liver in which the small bile ducts are gradually destroyed, causing bile and other toxins to build up ...

Seladelpar, an investigational selective agonist of peroxisome proliferator–activated receptor-delta (PPAR-δ), significantly improves liver biomarkers of disease activity and bothersome symptoms of ...

—A recent study provides genetic evidence linking a higher body mass index (BMI) to an increased risk of primary biliary cholangitis and autoimmune hepatitis but a decreased risk of primary sclerosing ...

A major retrospective study shows that people with blood group A face a higher likelihood of autoimmune liver disease, especially primary biliary cholangitis, while those with blood group B appear ...

Recurrent primary biliary cholangitis (rPBC) occurs in a significant number of patients following liver transplantation for PBC. Various immunosuppressive therapies and ursodeoxycholic acid treatment ...