FierceBiotech

PD-1 inhibitor R&D tapering off as newer oncology molecules capture attention: IQVIA

Move over PD-1, your time has passed. At least, that’s the sense from IQVIA’s latest report, which suggests development of immuno-oncologics such as PD-1/PD-L1 checkpoint inhibitors has started to ...
Forbes

A Deeper Look at Anti-PD-1/PD-L1 Checkpoint Inhibitors for Cancer

When many cancers advance, spread and reoccur, checkpoint inhibitors can help keep difficult tumors at bay. These antibody-based immunotherapies can restore the body’s ability to recognize and ...
ascopubs.org

PD-1/PD-L1 Inhibitor Plus Chemotherapy Versus PD-1/PD-L1 Inhibitor in Microsatellite Instability Gastrointestinal Cancers: A Multicenter Retrospective Study

To investigate the efficacy of PD-1/PD-L1 inhibitors plus chemotherapy versus anti–PD-1/PD-L1 monotherapy in advanced microsatellite instability (MSI)/mismatch repair-deficient (dMMR) gastrointestinal ...
ascopubs.org

Functional Engagement of the PD-1/PD-L1 Complex But Not PD-L1 Expression Is Highly Predictive of Patient Response to Immunotherapy in Non–Small-Cell Lung Cancer

Novel Prognostic Staging System for Patients With De Novo Metastatic Breast Cancer The multisite blinded analysis across a cohort of 188 immune checkpoint inhibitor-treated patients demonstrated the ...
FiercePharma

Fierce Pharma Asia—AstraZeneca eyes China's innovation, plots Singapore ADC plant; FDA rejects Hengrui's PD-1 drug

AstraZeneca's CEO wants to tap into China's innovation explosion. The company inked an oncology antibody deal with Harbour BioMed, and it plans to build a $1.5 billion ADC plant in Singapore. Hengrui ...
The American Journal of Managed Care

Will Subcutaneous PD-1/PD-L1 Inhibitors Be a Game Changer?

With Bristol Myers Squibb (BMS) now rolling out the SC version of rival nivolumab (Opdivo Qvantig), the shift from 30-minute intravenous (IV) infusion to 5-minute SC injection could be one of the most ...