Nature

Single-strand conformation polymorphism analysis using capillary array electrophoresis for large-scale mutation detection

This protocol describes capillary array electrophoresis single-strand conformation polymorphism (CAE-SSCP), a screening method for detection of unknown and previously identified mutations. The method ...
Nature

Heteroduplex analysis by capillary array electrophoresis for rapid mutation detection in large multiexon genes

The main goal of the molecular diagnosis of hereditary diseases is the identification of disease-causing mutations with a view to detecting carrier individuals who may benefit from early diagnosis, ...
GEN

Genotyping Using CGE

Nucleic acid analysis, genotyping, PCR, and RFLP methodologies are time-consuming techniques using agarose or acrylamide gel electrophoresis—image capture plus gel image interpretations. Capillary gel ...
technologynetworks

An Introduction to Capillary Electrophoresis: Theory, Practice, and Applications

Capillary electrophoresis (CE) is the name of a family of analytical techniques that involve the separation of charged molecules within a narrow capillary tube under the influence of an electric field ...
News Medical

Determining Microsatellite Instability Status Using Multiplex PCR-Based Methods

Please give an overview of microsatellite instability (MSI) status and its applications within oncology. Historically Microsatellite Instability (MSI) has been used to screen for Lynch Syndrome, a ...