Mendelian randomization is a method for causal inference that leverages the random inheritance of alleles as instrumental variables to estimate the causal effects of exposures on outcomes 1,2,3,4 (Box ...
Introduction to Mendelian randomization, the problems with using traditional observational studies to investigate causality, and Randomized controlled trials as the gold standard for causal research.
In 1812, the British ophthalmologist James Ware relayed a curious finding to the members of the Royal Society in London. Of thousands of young men recruited to regiments of the British army, only six ...
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