Cancer is often defined by its complexity: countless mutations, shifting cell populations, and tumors that evolve under ...

A cell copies all of its DNA, gears up to split in two, and then just… doesn’t. It sits there, swollen with a double genome, and nobody notices. This kind of silent failure has been observed in labs ...

Scientists have identified an unexpected source of genetic variation in human sperm that occurs earlier in sperm development than previously thought. Published in Nature, researchers at the Wellcome ...

How readily a cell divides and how well it survives are fundamental to life, shaping everything from organ size to the body's ability to withstand disease. That combination, known as cell fitness, isn ...

Scientists have recently been learning more about the importance of small bits of circular genetic material known as extrachromosomal DNA (ecDNA). These little circles of DNA can hitch a ride with ...

In each cell of your body, DNA is stored in structures called chromosomes. When cells divide, these chromosomes are copied, but over time, the copying process degrades. After many cycles of making ...

The enzyme cyclin-dependent kinase 1 (CDK1) and its partner cyclin B1 were thought to be sufficient to achieve error-free cell division. But now CDK5, an atypical cyclin-dependent kinase mostly known ...

Researchers at the University of Liverpool have discovered that SYCP1, a protein previously thought to function only during the production of sperm and eggs, can be reactivated in cancer cells, where ...

If scientists could shrink themselves to microscopic size and take a journey through the human body—like the submarine crew in the 1966 science fiction classic "Fantastic Voyage"—one of their first ...

A new study shows that restricting calorie intake in mice resulted in fewer DNA mutations as they age. Researchers found fewer mutations in tissue and | Genetics ...