A single dose of a cancer-causing chemical, given to mice at 15 days of age, produced strikingly different tumors depending ...

Gene editing is a highly precise and powerful technology that allows scientists to insert, delete, modify or replace DNA ...

The human genome contains more than 20,000 genes. However, at any given time and in a given cell, only a fraction are active.

Deep learning approaches have transformed how scientists predict the activity and function of DNA sequences in the genome. A ...

A lot of effort has gone into finding ways to minimize or eliminate off-target edits. In a recent issue of Nature, ...

Imagine being able to edit disease out of a person's DNA.

Enhancers are pieces of DNA that act like switches, regulating when genes are turned on and off and how strongly they are activated.

A baby can inherit one healthy copy of TBX5 and still develop serious heart defects if the other copy does not work. That genetic imbalance is one cause of congenital heart disease, the most common ...

A new study has discovered in mouse models that genes associated with repairing mismatched DNA are critical in eliciting damages to neurons that are most vulnerable in Huntington's disease and ...

The small study in patients with a rare disorder that causes liver and lung damage showed the potential for precisely targeted infusions. By Gina Kolata See more of our coverage in your search results ...