A hormone called FGF21 can reverse obesity in mice by activating a newly identified brain circuit tied to metabolism. Surprisingly, it works in the hindbrain—the same region targeted by GLP-1 drugs ...

Most metabolic discussions focus on calories and hormones — but FGF21 may sit higher up the chain. In this deep dive, we ...

Pancreatitis represents one of the most common and debilitating diseases of the gastrointestinal tract, resulting from premature activation of digestive enzymes in the pancreas, which causes tissue ...

Researchers have found that the hormone FGF21 reversed obesity in mice by acting on a newly identified brain circuit in the hindbrain. Unlike GLP-1 drugs, which mainly reduce appetite, FGF21 appears ...

A pioneering research study published today in Cell Metabolism details how the hormone FGF21 (fibroblast growth factor 21) can reverse the effects of fatty liver disease in mice. The hormone works ...

Fibroblast growth factor 21 (FGF21), a hepatokine, has been implicated in preference for sweet foods in humans for the first time. Previous work in rodents had shown that FGF21 secreted from the liver ...

Scientists have discovered a way to extend the lives of lab mice by 40 percent and suggest that it could one day be used as a treatment to boost human lifespans. In a study published this week in the ...

A hormone that extends lifespan in mice by 40% is produced by specialized cells in the thymus gland, according to a new study by Yale School of Medicine researchers. The team also found that ...

Strength training and cardio exercise affect the body differently with regard to the types of hormones they release into the blood, new research shows. One of the conclusions of the study is that ...