Skeletal stem cells (SSCs) are essential for bone development, homeostasis, and repair. Recent studies have identified distinct SSC populations in long bones, craniofacial bones, and spine. Techniques ...

Gestational growth and development of bone is an understudied process compared to soft tissues and has implications for lifelong health. This study investigated growth and development of human fetal ...

Osteoarthritis (OA) is a degenerative joint disease affecting millions of people worldwide 1. It is characterized by chronic pain that leads to disability, and loss of joint motion, thus reducing ...

Blood cancers such as leukemia are caused by genetic changes in the blood-forming stem cells of the bone marrow. Scientists at the University Medical Center Mainz have now shown how chronic ...

Rather than completely blocking all downstream signals, the peptide developed in this study focuses on inhibiting the activation of p38-MAPK. This is enough to downregulate the development of mature ...

The first 'blueprint' of human skeletal development reveals how the skeleton forms, shedding light on the process of arthritis, and highlighting cells involved in conditions that affect skull and bone ...

If you have ever broken a bone, you quickly learn two things: it hurts a lot, and bones are living tissue that takes time to heal, but they do heal. A fractured femur, for instance, may take six ...

There is a complex pathological relationship between diabetes and osteoporosis, two of the most common chronic diseases worldwide.

The oldest collection of mass-produced prehistoric bone tools reveal that human ancestors were likely capable of more advanced abstract reasoning one million years earlier than thought, finds a new ...

Your skin tends to steal the spotlight in the summer — it needs a lot of SPF and TLC to stay healthy. But don’t forget about ...