Chaperone-mediated autophagy (CMA) contributes to regulation of energy homeostasis by timely degradation of enzymes involved in glucose and lipid metabolism. Here, we report reduced CMA activity in ...
DECEMBER 3, 2025—(BRONX, NY)—Two related studies published today in Nature Metabolism show that a specialized intracellular recycling mechanism—chaperone-mediated autophagy (CMA)—is essential for ...
Researchers decipher mechanism that prevents the loss of brown adipose tissue activity during ageing
From left to right, Tania Quesada-López, Francesc Villarroya, Albert Blasco-Roset, Marta Giralt, Alberto Mestres-Arenas, Joan Villarroya, Aleix Gavaldà-Navarro and Rubén Cereijo. As the body ages, ...
As the body ages, brown adipose tissue activity decreases, fewer calories are burned, and this can contribute to obesity and certain chronic cardiovascular diseases that worsen with age. A study led ...
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