This paper considers a biologically relevant question of a Gaussian chain (such as an unfolded protein) binding to a sequence of receptors with matching multiple ligands distributed along the chain.

Ubiquitin-specific protease (USP) 25, belonging to the USP family of deubiquitinases, harbors two tandem ubiquitin-interacting motifs (UIMs), a ~20-amino-acid α-helical stretch that binds to ubiquitin ...

Scientists at Tokyo Institute of Technology have discovered a unique molecular mechanism responsible for the substrate preference of ubiquitin-specific proteases. Researchers at Tokyo Institute of ...

Everyday objects such as metal chains, handcuffs, and key rings are examples that demonstrate a unique combination of properties where hard, rigid rings are interlocked together to exhibit flexibility ...