Loss of function of the CFTR anion channel leads to cystic fibrosis, the most common inherited condition in humans of European origin. A recently reported structure for CFTR at 3.7-Å resolution ...
Scientists at St. Jude Children's Research Hospital and Rockefeller University have combined their expertise to gain a better understanding of the cystic fibrosis transmembrane conductance regulator ...
(Memphis, Tenn.—March 22, 2023) Scientists at St. Jude Children’s Research Hospital and Rockefeller University have combined their expertise to gain a better understanding of the cystic fibrosis ...
Scientists studying the protein that, when defective or absent, causes cystic fibrosis has made an important discovery about how that protein is normally controlled and under what circumstances it ...
“The structure of CFTR resembles a turnstile it has a pathway for chloride movement across the cell border and a gate that controls access to this pathway. Turning of the gate is powered by adenosine ...
A DFG-funded project led by Dr. Manuel Nietert from Göttingen and PD. Dr. Frauke Stanke from Hannover has developed a database for substances tested for their effects on CFTR function. The data was ...
Pharmacology has a cation bias. For too long, research has focused heavily on sodium and potassium channels, often treating anion transport as a secondary ...
The cystic fibrosis transmembrane conductance regulator has been studied for years but the new efforts have yielded important insights. Scientists at St. Jude Children's Research Hospital and ...
A team of researchers studying the protein that, when defective or absent, causes cystic fibrosis (CF) has made an important discovery about how that protein is normally controlled and under what ...
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