Merck & Co., Inc. MRK announced that it is not going ahead with filing the regulatory applications seeking approval for anacetrapib, a cholesteryl ester transfer protein (CETP) inhibitor that it had ...

Please provide your email address to receive an email when new articles are posted on . CETP inhibition may help high-risk patients reach their LDL goals and reduce risk for atherosclerotic CVD events ...

January 29, 2009 (Boston, Massachusetts) — A new analysis of the Women's Genome Health Study has found that common variants in the gene coding for cholesterol ester transfer protein (CETP) have an ...

Please provide your email address to receive an email when new articles are posted on . Incidence of major coronary events was significantly reduced among patients with atherosclerotic vascular ...

Within the past few years, a class of drugs known as cholesteryl ester transfer protein (CETP) inhibitors have been under investigation for their potential to increase HDL-C levels and, in effect, ...

It all began with a New England Journal of Medicine publication that appeared on November 1, 1990. The paper, entitled “Increased High-Density Lipoprotein Levels Caused By A Common Cholesteryl-Ester ...

The rationale for targeting cholesteryl ester transfer protein (CETP), an enzyme that promotes the transfer of cholesteryl esters from HDL to very low-density lipoprotein and LDL, to reduce the risk ...

In 2003, Pfizer purchased Esperion Therapeutics for $1.3 billion for access to Esperion’s experimental medicine, ETC-216, an early-stage synthetic, biological drug that mimicked the beneficial effects ...

Merck & Co., Inc.MRK announced detailed data from a large phase III cardiovascular outcomes study (REVEAL) evaluating anacetrapib, a cholesteryl ester transfer protein (CETP) inhibitor in patients ...

This is one of our periodic Five Year Watch columns, examining whether and why predictions of scientific progress were accurate, or hype. Five years ago, a new class of cholesterol-lowering drugs was ...

A timely study in this issue reports the high-resolution crystal structure of the human plasma protein cholesteryl ester transfer protein (CETP) with its natural lipid ligands. The crystal structure ...