Immunologists have identified a previously unrecognized group of immune cells that could reshape how vaccines and immune-based therapies are designed. The newly described cells 1 are long-lived memory ...

Detailed mapping of CD4⁺ T cells from children with systemic lupus erythematosus (SLE) has revealed distinct immune cell subsets with likely roles in disease pathogenesis, according to a study led by ...

Northwestern Medicine scientists have identified the cellular mechanisms that cause immune cells to differentiate and ultimately lose function during viral infection, findings that could improve ...

Introduction Patients with SLE have an increased risk of infections and infection-related mortality, which may be associated ...

New research shows how a specially trained population of immune cells keeps the peace by preventing other immune cells from attacking their own. The study provides a better understanding of immune ...

During infections, the immune system needs to distinguish foreign molecules from invading bacteria and viruses from molecules that are made by cells of the body. If it can’t, the immune system can ...

The brain and spinal cord were once thought to enjoy immune privilege, meaning they were believed to be largely insulated from immune activity elsewhere in the body. In recent years, however, ...

CD4 counts show how strong your immune system is; lower counts mean a weaker immune response. The CD4 percentage shows what part of your white blood cells are CD4 cells and helps check how strong your ...

In a recent study published in Proceedings of the National Academy of Sciences, researchers engineered Chimeric Antigen Receptor (CAR) CD4 T cells, a technology originally revolutionized for cancer ...

During infections, the immune system needs to distinguish foreign antigens that are expressed by invading bacteria and viruses from self-antigens that are expressed by cells of the body. If not, the ...