High-fat diet (HFD) feeding in mice promotes induction of aldose reductase (AR) activity, expression, and senescence of adipocytes in subcutaneous adipose tissue (scAT), according to a new study in ...
Aldose reductase, a key enzyme in the polyol pathway, catalyses the conversion of glucose to sorbitol, a process that becomes particularly problematic in hyperglycaemic conditions. Excessive flux ...
ATLANTA, GA — A multicenter controlled trial testing the ability of an aldose reductase inhibitor to stabilize early-stage asymptomatic diabetic cardiomyopathy missed its primary endpoint, researchers ...
Diabetes. 2005;54(6):1615-1625. The polyol pathway, shown schematically in Fig. 2, focuses on the enzyme aldose reductase. Aldose reductase normally has the function of reducing toxic aldehydes in the ...
High-fat diet (HFD) feeding in mice promotes induction of aldose reductase (AR) activity, expression, and senescence of adipocytes in subcutaneous adipose tissue (scAT), according to a new study in ...
Glucide comportant un groupe aldéhyde (-CHO). L'étude des aldoses n'a cessé de se renouveler à mesure que les techniques d'analyse moléculaire et de biochimie s'affinaient. Les recherches récentes se ...
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