Ataxia-telangiectasia mutated (ATM) and RAD3-related (ATR) is a member of the phosphoinositide 3-kinase (PI3K)-related family of protein kinases, which includes ATM, that regulates DNA-damage ...
Berzosertib (formerly M6620, VX-970) is a highly potent and selective, first-in-class inhibitor of ataxia telangiectasia and Rad3-related protein kinase (ATR). We assessed multiple ascending doses of ...
A phase 1/2 study of the TORC1/2 inhibitor onatasertib combined with toripalimab in patients with advanced solid tumors: Cervical cancer cohort.